Police investigate a multi-vehicle collision in Yarra Glen

Police are investigating a serious crash which occurred in Yarra Glen.

Major Collision Investigation Unit detectives are investigating a multi-vehicle collision in Yarra Glen which occurred on Friday night that has left a driver in a critical condition.

Investigators have been told a Mitsubishi sedan was travelling east-bound on Healesville-Yarra Glen Road when it veered onto the wrong side of the road just before 11.30pm on Friday, 28 October.

A Mazda utility travelling in the opposite direction swerved to avoid the Mitsubishi and a Mazda SUV narrowly avoided a collision, spinning out of control onto a nearby driveway.

The Mitsubishi then collided with an oncoming Nissan utility.

The driver of Nissan, an 83-year-old Mount Evelyn man, was taken to hospital with life-threatening injuries.

The driver of the Mitsubishi, a 23-year-old Healesville woman, was taken to hospital with non-life-threatening injuries.

No one else was seriously injured.

The exact circumstances surrounding the collision are yet to be determined and investigations remain ongoing.

Anyone who witnessed the incident, has dashcam footage or any other information is urged to contact Crime Stoppers on 1800 333 000 or submit a confidential report online at www.crimestoppersvic.com.au